Avitaminosis C, as well as the state of increased need for ascorbic acid, hard work, a period of reconvalescence after severe diseases, scurvy, alcoholism, burn disease, prolonged hypothermia, prolonged fever, hyperthyroidism, chronic infections, gastrointestinal diseases (persistent diarrhea, small intestine resection, peptic Ulcer, gastrectomy), smoking, prolonged stressful condition, lactation period...